Alteration of Extracellular Matrix Molecules and Perineuronal Nets in the Hippocampus of Pentylenetetrazol-Kindled Mice

Figure 5

Quantitative analyses of extracellular matrix molecules in the PTZ-kindled mouse hippocampus. Quantified mean fluorescence intensity of PV-positive neurons (a), WFA-positive PNNs (b), and Cat-315-positive PNNs (c), in the mouse hippocampus. Quantified mean fluorescence intensity of WFA-positive molecules (d) and Cat-315-positive molecules, excluding PNNs, in the mouse hippocampus. All data are presented as the ( mice per group). The values indicate two-way ANOVA followed by Bonferroni -tests. . PV: parvalbumin; WFA: Wisteria floribunda agglutinin; PNN: perineuronal nets; PTZ: pentylenetetrazole.