Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype

Figure 4

Correlations between upper limb motor function at three months after stroke and tract-related fractional anisotropy at three months after stroke in (a) valine (Val) homozygotes and (b) methionine (Met) allele carriers of BDNF genotype. “” represents the partial correlation coefficient. Asterisks indicate significant differences (). CC: corpus callosum; CST: corticospinal tract; FA: fractional anisotropy; FMA-UE: Fugl-Meyer assessment, upper extremity; M1PMv: intrahemispheric corticocortical connection from the primary motor cortex to the ventral premotor cortex; : partial correlation coefficient; T1: two weeks after stroke onset; T2: three months after stroke onset.

(a)

(b)