Exercise-Induced Adaptations to the Mouse Striatal Adenosine System

Figure 2

Striatal ENT1, D₂R, and D₁R protein expression following eight weeks of wheel running. Representative immunohistochemistry images for ENT1 in the mouse striatum following eight weeks of (a) sedentary conditions and (b) running wheel access. (c) Relative levels of ENT1 protein density represented as averages across sections as detailed in Methods. Representative immunohistochemistry images for D₂R in the mouse striatum following eight weeks of (d) sedentary conditions and (e) running wheel access. (f) Relative levels of D₂R protein density represented as averages across sections detailed in Methods. Representative immunohistochemistry images for D₁R in the mouse striatum following eight weeks of (g) sedentary conditions and (h) running wheel access. (i) Relative levels of D₁R protein density represented as averages across sections as detailed in Methods. Sedentary 8 weeks vs. runner 8 weeks at ^A and ^B.

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