Four Novel Variants in <i>POU4F3</i> Cause Autosomal Dominant Nonsyndromic Hearing Loss

<div>Pedigree, temporal bone CT, variant analysis, and audiogram of family A. (a) Affected subjects are denoted in black. Arrow shows the proband. (b) Temporal bone CT of the III:3 shows no structural change. (c) Chromatogram shows <i>POU4F3</i> heterozygous c.696G&gt;T detected in patients. (d) Audiograms of the affected subjects. Hearing loss appears to be highly heterogeneous (red: right ear; blue: left ear).</div>

Neural Plasticity

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Figure 1

Figure 1: Four Novel Variants in <i>POU4F3</i> Cause Autosomal Dominant Nonsyndromic Hearing Loss 

Neural Plasticity

Four Novel Variants in POU4F3 Cause Autosomal Dominant Nonsyndromic Hearing Loss

Figure 1