In Vivo Plasticity at Hippocampal Schaffer Collateral-CA1 Synapses: Replicability of the LTP Response and Pharmacology in the Long-Evans Rat

Figure 13

PQ10 enhanced the LTP response to the protocol. (a) Input/output curves showing no significant differences among groups. (b) PQ10-treated (green, ) subjects had increased fEPSPs during the 2-hour posttetanisation recording as compared to control (black, ). Values represent . Outsets above LTP curves represent average waveform field potentials during 30 min baseline prior to tetanisation and 0-30 min and 90-120 min posttetanisation. Horizontal bar: 1 mV; vertical bar: 5 ms. (c) PTP, STP, and LTP responses are presented as ; .

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