Noncanonical Roles of hα-syn (A53T) in the Pathogenesis of Parkinson’s Disease: Synaptic Pathology and Neuronal Aging

Figure 6

High hα-syn expression in the ipsilateral olfactory bulb. (a) Representative images showing mCherry-positive nerve fibers in the ipsilateral olfactory bulb at 3 months after viral injection. (b) Representative images showing hα-syn expression in the ipsilateral olfactory bulb by using immunohistochemistry at 3 months after viral injection. (c) Quantitative analysis of hα-syn expression in the ipsilateral olfactory bulb at 3 months after viral injection (). (d) Representative images showing mCherry-positive nerve fibers in the ipsilateral olfactory bulb at 7 months after viral injection. (e) Representative images showing hα-syn expression in the ipsilateral olfactory bulb by using immunohistochemistry at 7 months after viral injection. (f) Quantitative analysis of hα-syn expression in the ipsilateral olfactory bulb at 7 months after viral injection (). (g) Representative images showing positive β-gal staining in the olfactory bulb at 7 months after viral injection. (h) Number of β-gal-positive cells in the olfactory bulb at 7 months after viral injection (). compared with the control group.

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