Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit

<div>Role of <i>β</i>-adrenoceptors on antidepressant effect. All arrows indicate activation arrows. Gs: stimulating adenylate cyclase g protein; ATP: adenosine triphosphate; AC: adenylate cyclase; cAMP: cyclic adenosine monophosphate; PKA: protein kinase A; CREB: cAMP-response element-binding protein; BDNF: brain-derived neurotrophic factor; LTP: long-term potentiation; AMPA: <i>α</i>-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor.</div>

Neural Plasticity

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Figure 4

Figure 4: Neuropharmacological Effects of Mesaconitine: Evidence from Molecular and Cellular Basis of Neural Circuit 