Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion

<div>MSC transplantation reduced the expression levels of the autophagy-related proteins Beclin 1 and LC3 II and increased p62 expression levels in the hippocampus. (a) Representative western blots of Beclin 1, LC3 II, and p62 protein expressions in the hippocampus of the sham, HIBD, and HIBD+MSC groups following damage for 12 h and 24 h. (b–d) Quantification analysis of hippocampal protein expression levels normalized to <i>β</i>-actin. 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Neural Plasticity

fig1

Figure 1

Figure 1: Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion 

Figure 1 | Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion 