Research Article

Mesenchymal Stromal Cells Suppress Hippocampal Neuron Autophagy Stress Induced by Hypoxic-Ischemic Brain Damage: The Possible Role of Endogenous IL-6 Secretion

Figure 7

Summary diagram showing the role of IL-6 from MSCs in regulating hippocampal neuron autophagy in HIBD rats. In the current study, IL-6 from MSCs decreased p-AMPK protein expression levels to activate mTOR pathway phosphorylation, which in turn downregulated autophagy in the damaged hippocampal neurons.