Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study

<div>Spontaneous brain activity in patients with NAION and healthy participants Significant differences in activity were observed in patients with NAION in the left middle frontal gyrus, left middle cingulate gyrus, left superior temporal gyrus, left inferior parietal lobule, right lingual gyrus, left putamen/lentiform nucleus, and left superior parietal lobule (false discovery rate corrected, <svg height="9.9449pt" id="M71" style="vertical-align:-0.6369991pt" version="1.1" viewbox="-0.0498162 -9.3079 83.525 9.9449" width="83.525pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M390 111C344 68 312 56 269 56C212 56 118 102 118 241C118 346 175 401 241 401C277 401 312 388 342 360C350 352 355 349 361 349C372 349 394 371 394 392C394 403 391 411 378 422C362 436 329 449 288 449H287C250 449 190 432 138 392C71 341 37 274 37 197C37 90 112 -12 238 -12C297 -12 363 32 407 90L390 111Z"></path></g><g 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The mean ReHo values for NAION and NC groups (c). Abbreviations: NAION: nonarteritic anterior ischemic optic neuropathy; NCs: normal controls; ReHo: regional homogeneity; L: left; R: right.</div>

Neural Plasticity

fig1

Figure 1

Figure 1: Abnormal Regional Spontaneous Neural Activity in Nonarteritic Anterior Ischemic Optic Neuropathy: A Resting-State Functional MRI Study 