Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy

Figure 2

Pharmacological targets of mitochondria in auditory neuropathy. Pharmacological therapeutics of mitochondrial dysfunction to rescue auditory neuropathies are still limited. Proven therapeutic strategy targets are comprised of apoptosis inhibition, sirtuin mediators maintaining mitochondrial homeostasis and capability of metabolism, and antioxidants and free radical scavengers that are helpful to alleviate oxidative stress.