GPER-Deficient Rats Exhibit Lower Serum Corticosterone Level and Increased Anxiety-Like Behavior

<div>Distribution of GPER in the prefrontal cortex, hippocampus, and basal lateral amygdala. (a–c) Distribution of Tomato fluorescence (red) in the prefrontal cortex (PFC), the hippocampus (Hip), and the basolateral amygdala (BLA) in the GPER reporter (GPER Cre/tdTomato) mice. Green arrows indicate regions shown in higher magnification in the insets. (d–f) Distribution of GPER immunofluorescence (green) in mouse PFC, Hip, and BLA. Arrows point to positive staining. (g–i) Distribution of GPER immunofluorescence (green) in rat PFC, Hip, and BLA. 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Neural Plasticity

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Figure 4

Figure 4: GPER-Deficient Rats Exhibit Lower Serum Corticosterone Level and Increased Anxiety-Like Behavior 