Research Article
Bushen-Tiansui Formula Improves Cognitive Functions in an Aβ1–42 Fibril-Infused Rat Model of Alzheimer’s Disease
Figure 2
Oral administration of BTF rescues cognitive deficits in Aβ1–42 fibril-infused rats. (a) The schedule of the treatment schedule and behavioral evaluation. (B-E) BTF improved cognitive functions in Aβ1–42 fibril-infused rats. Rats ( or 9 per group) orally administered saline or BTF were trained in the water maze for 5 d. Data are presented as of latency to mount the escape platform (b), the AUC of latency (c), the percentage of time spent (d) (, ) and the number of crosses in the target quadrant (e) (, ). (f) Representative images of the swim paths of different rat groups in the hidden platform and probe tests. , by one-way ANOVA with Tukey’s multicomparison test compared with saline-treated Aβ1–42 fibril-infused rats.
| (a) |
| (b) |
| (c) |
| (d) |
| (e) |
| (f) |