Neural Plasticity

Review Article

Comparison of Different In Vivo Animal Models of Brachial Plexus Avulsion and Its Application in Pain Study

Table 1

Detailed overview of the in vivo models of brachial plexus avulsion.
Surgical approachAuthorshipPublication yearSpeciesType of avulsionResearch fieldRefs
Anterior avulsion approachRodrigues-Filho et al.2003RatsC8-T1 rootsNeuropathic pain[23]
Quintão et al.2008
2006		MiceC8-T1 rootsNeuropathic pain[13, 24]
Li et al.2015RatsC5-T1 rootsSC motor neuron apoptosis[25]
Liu et al.2016RatsC5-C6 roots
C5-T1 roots		Neuropathic pain[26]
Tan et al.2017RatsC7 rootNeuroprotective effect[27]
Wang et al.2015RatsC5-T1 rootsNeuropathic pain[28]
Paszcuk et al.2011MiceC8-T1 rootsNeuropathic pain[29]
Kobayashi et al.2015RatsC8-T1 rootsNeuropathic pain[30]
Zhao et al.2018RatsC8-T1 rootsNeuropathic pain[31]
Liu et al.2018RatsC5-T1 rootsNeuropathic pain[32]
Meng et al.2020RatsC5-T1 rootsNeuropathic pain[33]
Zhang et al.2020MiceC7 rootNeuropathic pain[34]
Posterior avulsion approachCao et al.2003RatsN. S.Anatomic and technical exploration[21]
Muñetón-Gómez et al.2004RatsC3-T3 rootsNerve regeneration[35]
Sim et al.2015RatsC7 rootSC motor neuron protection[36]
Gu et al.2004RatsC8 rootSC motor neuron regeneration[37]
Zarina et al.2016PigsC5-C7 rootsNeuropathological characteristics[38]
Zhang et al.2017RatsC5-T1 rootsMotor cortical reorganization[39]
Chen et al.2019MiceC5-C7 rootsSC motor neuron protection[40]
Zhang et al.2019RatsC5-C7 rootsSC motor neuron protection and reconstruction methods[41]
Huang et al.2020RatsC5-C7 rootsNerve regeneration[42]
Hou et al.2018RatsC5-T1 rootsNeuropathic pain[43]
Meng et al.2019RatsC5-T1 rootsNeuropathic pain[44]
Huo et al.2020RatsC5-T1 rootsNeuropathic pain[45]
Wang et al.2019RatsC5-T1 rootsNeuropathic pain[15]
Shen et al.2019RatsC5-T1 rootsNeuropathic pain[46]
Fang et al.2017RatsC5-T1 rootsSC motor neuron protection[47]
Closed avulsion approachSpinner et al.2000RatsN. S.Model establishment[48]
Yang et al.2015RatsN. S.Model establishment[49]
N. S. refers to the idea that there is no specific root avulsion statement or the ratio of different types of avulsion roots was analyzed in the articles. SC: spinal cord.