Heterogeneous Acupuncture Effects of Taixi (KI3) on Functional Connectivity in Healthy Youth and Elder: A Functional MRI Study Using Regional Homogeneity and Large-Scale Functional Connectivity Analysis

Table 2

Clusters of ReHo differences between postacupuncture state and resting-state fMRI.

Group	Peak MNI coordinate			Cluster voxels	Peak intensity	Lobe	BA	Structure (voxels)
	Youth
Cluster 1	18	-90	-6	51	-6.90	Occipital	\	Lingual_R (37)
Cluster 2	-54	-6	36	38	-5.15	Frontal	6	Postcentral_L (28)
								Precentral_L (10)
Cluster 3	6	-27	63	38	-5.93	Frontal	6	PCL_R (18)
								SMA_R (15)
Elder
Cluster 1	-48	-24	30	102	-4.94	Parietal	\	Postcentral_L (83)
							\	SupraMarginal_L (12)
Cluster 2	57	-9	33	64	-5.54	Frontal	\	Postcentral_R (61)
Cluster 3	-3	9	42	36	-5.12	Limbic	32	Cingulum_Mid_L (14)
								Cingulum_Mid_R (13)
Cluster 4	15	-39	69	62	-6.05	Parietal	3	Postcentral_R (38)
								PCL_R (15)
Cluster 5	15	-24	66	53	-5.81	Frontal	\	Precentral_R (10)
								SMA_R (26)
								SMA_L (9)

The location assignment has been done by using a MATLAB toolbox xjview (http://www.alivelearn.net/xjview). A paired test was used to compare the ReHo results between postneedling and resting state in healthy youth and elder groups, respectively. The statistical maps were GRF corrected at a voxel level and cluster level (one-tailed). Edge connected cluster connectivity criterion, . Those structures with a size greater than or equal to 9 voxels were reported. PCL: paracentral lobule; SMA: supplementary motor area; SupraMarginal: supramarginal gyrus; Cingulum_Mid: cingulum middle.