Aberrant Advanced Cognitive and Attention-Related Brain Networks in Parkinson’s Disease with Freezing of Gait

Figure 3

The correlations between brain regions connectivity abnormities and the severity of gait disorders symptoms in FOG+ patients. (a) Threshold maps for the TPS.L of the AUN. (b, c) Altered connectivity in the TPS.L correlated positively with GFQ score (, ) and FOGQ score (, ). (d) Threshold maps for the ANG.R of the DMN. (e, f) Altered connectivity in the ANG.R correlated positively with GFQ score (, ) and FOGQ score (, ). FOG+: Parkinson’s disease with freezing of gait; L/R: left/right hemisphere; AUN: auditory network; TPS: temporal pole: superior temporal gyrus; DMN: default mode network; ANG: angular gyrus; GFQ: Gait and Falls Questionnaire; FOGQ: Freezing of Gait Questionnaire.

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