Review Article
Acupuncture for Adults with Diarrhea-Predominant Irritable Bowel Syndrome or Functional Diarrhea: A Systematic Review and Meta-Analysis
Table 1
Basic information of the included studies.
| | Study ID | Sample size (T/C) | Mean age (years) | Diagnostic standards | Intervention | Comparison | Duration
(weeks) | Outcome | Adverse effects |
| | Qian et al. 2011 [20] | 120 (60/60) | T:
C: | Roman III | Acupuncture plus dicetel | Sham acupuncture plus dicetel | 4 | (2)(4)(6) | NR | | Sun et al. 2011 [21] | 63 (31/32) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)
(5)(6) | None | | Wang et al. 2011 [22] | 120 (60/60) | T:
C: | Roman III | Eye acupuncture | Dicetel | 4 | (2)(4)
(7)(9) | T: 6
C: 0 | | Chen et al. 2012 [23] | 64 (34/30) | T:
C: | Roman III | Electroacupuncture | Bacillus licheniformis plus deanxit | 4 | (2)(4)(7) | NR | | Li et al. 2012 [24] | 64 (32/32) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4) | NR | | Pei et al. 2012 [25] | 65 (33/32) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4) | NR | | Wu et al. 2013 [26] | 48 (24/24) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)(6) | NR | | Li et al. 2012 [27] | 70 (35/35) | T:
C: | Roman II | Acupuncture | Dicetel | 4 | (2)(4)
(6)(7) | NR | | Liu 2013 [28] | 60 (30/30) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)(9) | T: 5
C: 0 | | Zhan et al. 2013 [29] | 66 (33/33) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)
(5)(6) | NR | | Wu et al. 2014 [30] | 73 (36/37) | T:
C: | Roman III | Warm acupuncture | Bacillus licheniformis plus deanxit | 4 | (2)(4) | NR | | Li et al. 2014 [31] | 60 (30/30) | T: 31.5
C: 33.8 | Roman III | Acupuncture | Dicetel | 4 | (2) | NR | | Zheng et al. 2014 [32] | 348 (261/87) | T:
C: | Roman III | Acupuncture | Loperamide | 4 | (1)(2)
(3)(9) | T: 3
C: 0 | | Li et al. 2015 [33] | 40 (24/16) | T:
C: | Roman III | Electroacupuncture | Loperamide | 4 | (1)(2)
(3)(4) | NR | | Zheng et al. 2016 [34] | 448 (336/112) | T:
C: | Roman III | Electroacupuncture | Loperamide | 4 | (1)(2)
(3)(9) | T: 11
C: 0 | | Qin et al. 2017 [35] | 61 (31/30) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)(8) | None | | Li et al. 2017 [36] | 81 (54/27) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2)(4)
(8)(9) | T: 0
C: 1 | | Nie 2017 [37] | 100 (50/50) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2)(4) | NR | | Huang 2017 [38] | 56 (38/18) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2)(4)(7) | None | | Liang 2017 [39] | 34 (22/12) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2)(4)(8) | NR | | Zhong et al. 2018 [40] | 60 (30/30) | T:
C: | Roman III | Electroacupuncture | Loperamide | 9 | (1)(2)(3) | NR | | Yang et al. 2018 [41] | 180 (120/60) | T:
C: | Roman III | Acupuncture | Trimebutine maleate | 4 | (2)(4) | NR | | Zou et al. 2019 [42] | 72 (36/36) | T:
C: | Roman III | Warm acupuncture | Eosinophil-lactobacillus compound tablet | 3 | (2)(4)(6) | NR | | Meng 2019 [43] | 70 (35/35) | T:
C: | Roman IV | Acupuncture | Dicetel | 4 | (2)(4)
(8)(9) | T: 1
C: 5 | | Zhang 2019 [44] | 65 (33/32) | T:
C: | Roman III | Warm acupuncture | Dicetel | 4 | (2)(4)(8) | NR | | Lu 2019 [45] | 76 (38/38) | T:
C: | Roman III | Acupuncture | Dicetel | 4 | (2)(4)(6) | NR | | Mao 2019 [46] | 80 (40/40) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2)(4)(5)
(8)(9) | T: 2
C: 4 | | Lin 2019 [47] | 68 (34/34) | T:
C: | Compliant with
Roman III | Acupuncture plus Dicetel | Dicetel | 4 | (2)(4)(5) | None | | Li 2019 [48] | 60 (30/30) | T:
C: | Roman IV | Warm acupuncture | Dicetel | 8 | (2)(4) | NR | | Liu 2020 [49] | 70 (35/35) | T:
C: | Roman III | Acupuncture | Trimebutine maleate | 8 | (2)(4)(8) | NR | | Li et al. 2020 [50] | 392 (261/131) | T:
C: | Roman III | Acupuncture | Dicetel | 6 | (2) | NR |
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