Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss

Figure 3

Intergroup comparison of ROI-wise FC between the SSNHL and HC groups. FC between the lAG and lSCLC was significantly increased (a). FCs between the lPHG.p and ROIs mainly located in the bilateral temporal lobes and left frontal lobe were significantly increased (b). The -axis coordinates correspond to the numbers of the brain regions in the Harvard-Oxford Atlas. The -axis coordinates on the left indicate the FC value, while those on the right indicate the value. The red and blue curves indicate the mean FC values of the pair of ROIs in each group, and the shadow reflects the standard deviations. The black line indicates intergroup differences between each pair of ROIs, with a value less than 0.05 where the black line is below the green horizontal line. ROI-wise FCs with significant difference between the SSNHL and HC groups are presented in a node and edge graph (c). The yellow balls indicate the seed ROI, while the cyan balls indicate the ROIs with significantly different FC values. The size of the sticks corresponds to the -values from the two-sample -tests. SCLC: supracalcarine cortex; PHG: parahippocampal gyrus; SFG: superior frontal gyrus; ITG: inferior temporal gyrus; PCG: paracingulate gyrus; l: left; p: posterior division; to: temporooccipital part.

(a)

(b)

(c)