Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population
Table 1
Demographics and clinical features of the study participants.
Variables
Subject group
Age (y)
Male: female
No. cases
Percent (%)
Education level
<12
23 : 82
105
31.92
=12
24 : 50
74
22.49
>12
54 : 96
150
45.59
ApoE allele
Grade 1 ()
13 : 27
40
12.16
Grade 2 (3/3)
67 : 141
208
63.22
Grade 3 (2/4)
4 : 7
11
3.34
Grade 4 ()
17 : 53
70
21.28
Nature of work
Mental labor
70 : 150
220
66.87
Manual labor
10 : 27
37
11.25
Mixed labor
21 : 51
72
21.88
CHD
+
11 : 11
22
6.69
—
90 : 217
307
93.31
Diabetes
+
16 : 21
37
11.25
—
85 : 207
292
88.75
Hypertension
+
46 : 64
110
33.43
—
55 : 164
219
66.57
Stroke
+
8 : 16
24
7.29
—
93 : 212
305
92.71
Anemia
+
1 : 15
16
4.86
—
100 : 213
313
95.14
Thyroid dysfunction
+
7 : 14
21
6.38
—
94 : 214
308
93.62
COP
+
16 : 34
50
15.20
—
85 : 194
279
84.80
General anesthesia
+
20 : 56
76
23.10
—
81 : 172
253
76.90
Head trauma
+
4 : 7
11
3.34
—
97 : 221
318
96.66
FHD
+
17 : 65
82
24.92
—
84 : 163
247
75.08
Diagnosis
SCD
43 : 108
151
45.90
NC
58 : 120
178
54.10
Key: CHD: history of coronary heart disease; COP: carbon monoxide poisoning; FHD: family history of dementia; SCD: subjective cognitive decline; NC: normal controls.