Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population
Table 2
Comparison of urinary AD7c-NTP levels in different demographic characteristics groups, nonneurological disease groups, and different ApoE allele grade groups.
Variables
Subject group
AD7c-NTP (ng/mL)
H/Z
Education level
<12
0.5562 (0.5261)
0.233
0.890
=12
0.5165 (0.3971)
>12
0.5368 (0.3310)
Nature of work
Mental labor
0.5184 (0.3681)
2.902
0.234
Manual labor
0.6311 (0.6305)
Mixed labor
0.5711 (0.3899)
CHD
+
0.7921 (0.7347)
-2.854
0.004
—
0.5246 (0.3823)
Diabetes
+
0.6355 (0.5824)
-2.725
0.006
—
0.5211 (0.3889)
Hypertension
+
0.5232 (0.4389)
-0.014
0.989
—
0.5381 (0.3925)
Stroke
+
0.6267 (0.6099)
-1.738
0.082
—
0.5315 (0.3880)
Anemia
+
0.5784 (0.4786)
-0.079
0.937
—
0.5322 (0.4091)
Thyroid dysfunction
+
0.6241 (0.8910)
-0.245
0.806
—
0.5322 (0.3897)
COP
+
0.5964 (0.5298)
-0.392
0.695
—
0.5265 (0.3918)
General anesthesia
+
0.5665 (0.4077)
-0.776
0.438
—
0.5265 (0.4035)
Head trauma
+
0.4969 (0.2551)
-0.274
0.784
—
0.5342 (0.4212)
FHD
+
0.5417 (0.3776)
-0.442
0.658
—
0.5322 (0.4428)
Diagnosis
SCD
0.5483 (0.4838)
-1.359
0.174
NC
0.5164 (0.3667)
ApoE allele
Grade 1 ()
0.4368 (0.3392)
Grade 2 (3/3)
0.5287 (0.3656)
9.080
0.028
Grade 3 (2/4)
0.5580 (0.9201)
Grade 4 ()
0.6074 (0.6541)
Key: AD7c-NTP: Alzheimer-associated neuronal thread protein; CHD: history of coronary heart disease; COP: carbon monoxide poisoning; FHD: family history of dementia; SCD: subjective cognitive decline; NC: normal controls; Data in AD7c-NTP were shown in median (interquartile range).
