Review Article

Reproduction-Associated Hormones and Adult Hippocampal Neurogenesis

Table 1

Effects of different estrogen and progesterone treatments on the adult hippocampal neurogenesis of mammals.

TreatmentModel organismNeuron proliferationNeuron survivalReference

SD rats[58]
SD rats[59]
SD rats[60]
SD rats[61, 62]
SD rats[61, 63]
SD rats[64]
SD rats[65]
SD rats[66]
Wistar rats[67]
ICR mice[31]

Note: “OVX” indicates bilateral ovarian resection; the green bar indicates estrogen or estradiol benzoic acid; the red bar indicates estrone; the orange bar indicates progesterone; the purple bar indicates benzoic acid and progesterone. The up arrows indicate upregulation, the down arrows indicate downregulation, and the horizontal bars indicate no change. Abbreviations: E2: estradiol; BrdU: bromodeoxyuridine; EB: estradiol benzoate; FST: forced swimming test; P4: progesterone; SD rats: Sprague-Dawley rats.