Ultrasound-Guided Transforaminal Injections of Platelet-Rich Plasma Compared with Steroid in Lumbar Disc Herniation: A Prospective, Randomized, Controlled Study
Table 2
Longitudinal outcomes of pain degree and spinal function for the PRP group over time.
Outcome
Time
PRP group ()
value#
VAS (median (1st-3rd))
Baseline
6.0 (6.0-7.3)
Ref
1 week
5.0 (5.0-6.0)
0.887
1 month
3.0 (3.0-4.0)
<0.001
3 months
3.0 (3.0-3.0)
<0.001
6 months
3.0 (2.0-3.0)
<0.001
1 year
2.0 (1.0-3.0)
<0.001
value over time↑
<0.001
PPTs (kPa, median (1st-3rd))
Baseline
580.60 (557.92-601.01)
Ref
1 week
625.96 (571.53-716.68)
0.087
1 month
707.60 (612.35-780.18)
<0.001
3 months
725.75 (698.53-843.68)
<0.001
6 months
725.75 (694.00-823.27)
<0.001
1 year
730.28 (694.00-789.25)
<0.001
value over time↑
<0.001
ODI (%, median (1st-3rd))
Baseline
35.0 (26.4-44.0)
Ref
1 week
27.0 (20.0-40.0)
0.125
1 month
22.0 (14.3-42.5)
<0.001
3 months
20.0 (16.5-29.0)
<0.001
6 months
20.0 (14.0-29.0)
<0.001
1 year
19.0 (15.5-30.0)
<0.001
value over time↑
0.001
PRP: platelet-rich plasma; 1st-3rd: 1st-3rd quartiles; PPTs: pressure pain thresholds; VAS: visual analogue scale; ODI: Oswestry disability index. # value compares difference from baseline using post hoc test or Wilcoxon signed-rank test. ↑ value indicates significance of overall change over time using the Friedman test.
