Research Article

Transcriptomic Analysis Reveals an Altered Hcy Metabolism in the Stria Vascularis of the Pendred Syndrome Mouse Model

Figure 1

The dramatic morphological changes occurred in stria vascularis from Slc26a4-/- mice. (a) The scala media, formed by basilar membrane, lateral wall, and vestibular membrane, is significantly enlarged in Slc26a4-/- mice. SV: stria vascularis. The outline of stria vascularis, which is visualized through pigmentation in intermediate cells, is clearer in Slc26a4+/+ mice. (b) Marginal cells in stria vascularis from wildtype or Slc26a4-/- mice were coated on coverlips and sent for phalloidin staining.
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