Research Article

The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model

Table 1

DEGs related to Wnt pathway in DRG and SCDH of rats 28 days after CCD.

Gene symbolDescriptionlog2 fold changeDirection value

DRG
NpyNeuropeptide Y3.9458<0.001
Runx2Runt-related transcription factor 21.3276<0.001
Cthrc1Collagen triple helix repeat containing 12.3058<0.0001
DraxinDorsal inhibitory axon guidance protein2.3726<0.01
CpzCarboxypeptidase Z-1.2635<0.01
Kb15Type II keratin Kb15-1.9539<0.05
TnnTenascin N2.6944<0.01
Amer2APC membrane recruitment protein 2-1.8238<0.01
Pcdh20Protocadherin 201.7709<0.001
Pcdh8Protocadherin 8-1.1441<0.01
Myh3Myosin heavy chain 3-1.9875<0.05
Gnb3G protein subunit beta 3-1.0005<0.05

SCDH
MccColorectal mutant cancer protein-2.2131<0.05
EgfEpidermal growth factor1.1111<0.0001
Cdh1Cadherin 11.7580<0.05
Plekha4Pleckstrin homology domain containing A41.4888<0.001