Research Article
The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model
Table 1
DEGs related to Wnt pathway in DRG and SCDH of rats 28 days after CCD.
| Gene symbol | Description | log2 fold change | Direction | value |
| DRG | Npy | Neuropeptide Y | 3.9458 | ↑ | <0.001 | Runx2 | Runt-related transcription factor 2 | 1.3276 | ↑ | <0.001 | Cthrc1 | Collagen triple helix repeat containing 1 | 2.3058 | ↑ | <0.0001 | Draxin | Dorsal inhibitory axon guidance protein | 2.3726 | ↑ | <0.01 | Cpz | Carboxypeptidase Z | -1.2635 | ↓ | <0.01 | Kb15 | Type II keratin Kb15 | -1.9539 | ↓ | <0.05 | Tnn | Tenascin N | 2.6944 | ↑ | <0.01 | Amer2 | APC membrane recruitment protein 2 | -1.8238 | ↓ | <0.01 | Pcdh20 | Protocadherin 20 | 1.7709 | ↑ | <0.001 | Pcdh8 | Protocadherin 8 | -1.1441 | ↓ | <0.01 | Myh3 | Myosin heavy chain 3 | -1.9875 | ↓ | <0.05 | Gnb3 | G protein subunit beta 3 | -1.0005 | ↓ | <0.05 |
| SCDH | Mcc | Colorectal mutant cancer protein | -2.2131 | ↓ | <0.05 | Egf | Epidermal growth factor | 1.1111 | ↑ | <0.0001 | Cdh1 | Cadherin 1 | 1.7580 | ↑ | <0.05 | Plekha4 | Pleckstrin homology domain containing A4 | 1.4888 | ↑ | <0.001 |
|
|