The Interaction Effects of Suicidal Ideation and Childhood Abuse on Brain Structure and Function in Major Depressive Disorder Patients

Table 2

Differences in GMV.

Group 1 : Group 2	Region	Voxel	MNI coordinates			values
			MDD1 : MDD-CTQ	Cuneus (L)	407		-10.5	-79.5	39.0	-3.8990
MDD3 : MDD-PA	Paracentral lobule (L)	534	-9.0	-37.5	66.0	-3.9553
MDD4 : MDD-SA	Frontal-Inf-Tri (L)	642	-46.5	28.5	7.5	4.1578
MDD5 : MDD-EN	Cuneus (L)	201	-10.5	-79.5	28.5	-4.0525
	Precuneus (L)	628	-4.5	-52.5	52.5	4.5582
MDD6 : MDD-PN	Cuneus (L)	225	-18.0	-70.5	22.5	-3.5359
MDD : MDD-SI	Lingual (R)	184	13.5	-48.0	-3.0	3.7768
SICTQ^a	Caudate (L)	77	-16.5	21.0	10.5	13.5885

^aInteraction effect of SI and childhood abuse. Notes: MDD patients without any kind of childhood abuse (MDD1); MDD patients with any kind of childhood abuse (MDD-CTQ); MDD patients without physical abuse (MDD3); MDD patients with physical abuse (MDD-PA); MDD patients without sexual abuse (MDD4); MDD patients with sexual abuse (MDD-SA); MDD patients without emotional neglect (MDD5); MDD patients with emotional neglect (MDD-EN); MDD patients without physical neglect (MDD6); MDD patients with physical neglect (MDD-PN); MDD patients without suicidal ideation (MDD); MDD patients with suicidal ideation (MDD-SI).