Neural Plasticity / 2021 / Article / Fig 4

Research Article

The Protective Role of E-64d in Hippocampal Excitotoxic Neuronal Injury Induced by Glutamate in HT22 Hippocampal Neuronal Cells

Figure 4

Effect of E-64d on glutamate-induced changes in mitochondrial membrane potential in terms of JC-1 activity and oxidative stress, as detected via ELISA. (a) Measurement of mitochondrial membrane potential via flow cytometry. (b) Quantitative analysis of mitochondrial membrane potential in HT22 cells. (c) Quantitative analyses of the average levels of 8-OHdG in cells. Three independent experiments were performed, and the data are expressed as the . vs. the Control group. ## vs. the Glutamate group. n.s.: not significant.

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