Research Article

Noise Exposure Alters Glutamatergic and GABAergic Synaptic Connectivity in the Hippocampus and Its Relevance to Tinnitus

Table 1

VGAT labeling in the hippocampus was decreased significantly in most areas two weeks after noise exposure with -test.

AreaLayer value
IpsilateralContralateral

DGMolecular layer—distal>0.05>0.05
Molecular layer—middle≤0.01≤0.05
Molecular layer—proximal≤0.01>0.05
Granule cell layer≤0.001≤0.001
Hilus≤0.001≤0.001
CA3Oriens≤0.001≤0.001
Pyramidale≤0.001≤0.001
Lucidum≤0.001≤0.001
Radiatum≤0.001≤0.01
CA1Oriens≤0.001≤0.001
Pyramidale≤0.001≤0.001
Radiatum—proximal≤0.001≤0.001
Radiatum—distal≤0.01≤0.01
Lacunosum—moleculare≤0.05>0.05