Review Article
Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies
Table 1
Clinical characteristics of subjects in the included studies.
| | Study | Cases (T/C) | Participant | Comparison | Intervention | Outcome measures | | Condition | Lesion location | Duration (days) | Age (years) | Gender (male/female) | T | C | Acupoints | Regimen | Analysis of fMRI | Coordinate | Secondary outcomes |
| | Zhengfei Ye 2018 | 84 (42/42) | Poststroke limb motion dysfunction | Unclear | Not reported | T:
C: | T: 22/20
C: 24/18 | Acu+Conv | Conv | LYDDM | 7/week for 2 weeks | ReHo | MNI | FMA, BI | | Zhihong Chen 2016 | 60 (30/30) | Poststroke limb motion dysfunction | Unclear | T:
C: | T:
C: | T: 17/13
C: 16/14 | Acu+Conv | Conv | LYDDM | 7/week for 2 weeks | ReHo | MNI | IFMA, BI | | Zhihong Chen 2016 | 60 (30/30) | Poststroke limb motion dysfunction | Unclear | T:
C: | T:
C: | T: 18/12
C: 16/14 | Acu+Conv | Conv | XNKQ | 7/week for 2 weeks | ReHo | MNI | FMA, BI | | Nana Chen 2017 | 12 (6/6) | R limb motion dysfunction | L basal ganglia or corona radiata | T:
C: | T:
C: | T: 2/4
C: 4/2 | Acu+Conv | Sham acu+Conv | Empirical acupoints | 7/week for 2 weeks | ReHo | MNI | FMA, MBI | | Ping Wu 2017 | 21 (11/10) | Poststroke limb motion dysfunction | Unclear | T:
C: | T:
C: | T: 7/4
C: 5/5 | Acu+Conv | Conv | Empirical acupoints | 5/week for 4 weeks | ReHo | Tal | NSD, FMA, MBI | | Ximei Xie 2012 | 20 (10/10) | R limb motion dysfunction | Pons or thalamus or L basal ganglia | T:
C: | T:
C: | T: 6/4
C: 5/5 | Acu+Conv | Conv | Empirical acupoints | 5/week for 4 weeks | ReHo | Tal | NDS, FMA, BI | | Yumei Zhou 2015 | 21 (11/10) | R limb motion dysfunction | L basal ganglia | T:
C: | T:
C: | T: 7/4
C: 4/6 | Acu+Conv | Conv | Empirical acupoints | 5/week for 4 weeks | ReHo | MNI | NSD, FMA, MBI |
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Abbreviations: Acu: acupuncture treatment; BA: Brodmann area; BI: Barthel index; C: control group; Conv: conventional treatment; FMA: Fugl-Meyer assessment; BMI: modified Barthel index; LYDDM: lifting yang to dredging du meridian needling method; MNI: Montreal Neurological Institute; R: right; ReHo: regional homogeneity; S: sensitivity; SDM: signed differential mapping; T: treatment group; XNKQ: Xingnao Kaiqiao needling method.
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