Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies

Table 2

Brain activity changes in patients after treatment compared to baseline.

	MNI coordinates			SDM -score^a	value^b	Voxels^c	Cluster breakdown
	Treatment group
R basal ganglia	34	-12	8	6.622	<0.05	1244	R lenticular nucleus, putamen, striatum, insula, rolandic operculum, BA48	0.88%
L insula	-32	-14	10	5.232	<0.05	887	L insula, lenticular nucleus, putamen, rolandic operculum, BA48	1.02%
L precentral gyrus	-28	-24	66	-4.477	<0.05	337	L precentral gyrus, corpus callosum, superior frontal gyrus, dorsolateral, BA6	5.83%
R superior frontal gyrus	22	2	62	-4.723	<0.05	20	Right superior frontal gyrus, dorsolateral, BA6	7.40%
Control group
R middle frontal gyrus	38	-6	56	5.457	<0.05	575	R middle frontal gyrus, superior frontal gyrus, dorsolateral, BA6	0.42%
L supplementary motor area	-6	4	66	4.867	<0.05	83	L supplementary motor area, BA6	1.29%
L basal ganglia	-24	0	-6	-4.876	<0.05	249	L lenticular nucleus, putamen, striatum, insula, BA48	0.09%
L inferior frontal gyrus	-32	32	-14	-5.547	<0.05	166	L inferior frontal gyrus, orbital part, BA47	0.52%

^aPeak height threshold: . ^bVoxel probability threshold: uncorrected and remained after correcting threshold (TFCE) of . ^cCluster extent threshold: voxels. Abbreviations: BA: Brodmann area; : heterogeneity ; MNI: Montreal Neurological Institute; R: right; ReHo: regional homogeneity; SDM: signed differential mapping.