Microglial Activation of GLP-1R Signaling in Neuropathic Pain Promotes Gene Expression Adaption Involved in Inflammatory Responses

<div>Schematic diagram of the rat operation and behavioural testing (a). Effects of glucagon-like peptide 1 receptor agonist exenatide in the activation of microglia in SNL-induced rats (b). Rats with spinal nerve ligation-induced neuropathy, received intrathecal injections of vehicle, exenatide (100 ng), or pretreatment of minocycline (100 <i>μ</i>g) 4 h. 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Neural Plasticity

fig1

Figure 1

Figure 1: Microglial Activation of GLP-1R Signaling in Neuropathic Pain Promotes Gene Expression Adaption Involved in Inflammatory Responses 