Increased Homotopic Connectivity in the Prefrontal Cortex Modulated by Olanzapine Predicts Therapeutic Efficacy in Patients with Schizophrenia

Figure 1

Brain regions with significant difference in VMHC between patients at baseline and healthy controls. Brain regions with significant difference in VMHC were the orbital IFG/STG, fusiform gyrus/cerebellum VI, STG, MTG/angular gyrus, opercular IFG, superior and middle MPFC, superior/middle MPFC, precentral gyrus/postcentral gyrus, precuneus, medial orbital FG, precentral gyrus, and median cingulum gyrus. The color bar represents the values of the group analysis of VMHC. VMHC = voxel-mirrored homotopic connectivity; IFG = inferior frontal gyrus; STG = superior temporal gyrus; MPFC = medial prefrontal cortex; MTG = middle temporal gyrus; FG = frontal gyrus.