Increased Homotopic Connectivity in the Prefrontal Cortex Modulated by Olanzapine Predicts Therapeutic Efficacy in Patients with Schizophrenia

Table 1

Characteristics of the subjects.

	Patients	Controls	/	value
Sex (male/female)	15/5	14/6	0.125	0.723^a
Age (years)			-2.008	0.052^b
Years of education (years)			-2.428	0.020^b
Dose of olanzapine (mg/day)
At baseline
PANSS
Positive
Negative
General
TMT-A
BACS-SC
HVLT-R
WMS-SS
NAB-M
BVMT-R
CF-ANF
MSCIT
CPT-IP
After 8 weeks of treatment
PANSS
Positive
Negative
General
TMT-A
BACS-SC
HVLT-R
WMS-SS
NAB-M
BVMT-R
CF-ANF
MSCIT
CPT-IP

^aThe values were obtained by the chi-square test. ^bThe values were obtained by two-sample -tests. PANSS = positive and negative syndrome scale; TMT-A = Trail Making Test, part A; BACS-SC = Brief Assessment of Cognition in Schizophrenia Symbol Coding Test; HVLT-R = Hopkins Verbal Learning Test-Revised; NAB-M = Neuropsychological Assessment Battery-Mazes; WMS-SS = Wechsler Memory Scale Spatial Span; CF-ANF = Category Fluency-Animal Naming Fluency; BVMT-R = Brief Visuospatial Memory Test-Revised; MSCIT = Mayer-Salovey-Caruso Emotional Intelligence Test; CPT-IP = Continuous Performance Test-Identical Pairs.