Decreased Nucleus Accumbens Connectivity at Rest in Medication-Free Patients with Obsessive-Compulsive Disorder

Table 2

Regions with abnormal functional connectivity with the accumbens in patients with OCD.

Cluster location	Peak (MNI)			Number of voxels	value
	Seed: left accumbens
Bilateral OFC	3	39	−27	49	−4.4404
Bilateral MPFC	24	69	6	198	−6.2321
Bilateral lingual gyrus	−21	−96	−3	97	−4.5262
Bilateral precuneus	9	−72	42	62	−4.5731
Left superior parietal lobule	−27	−51	63	42	−3.9449
Seed: right accumbens
Left OFC	−9	63	−9	33	−4.0701
Right fusiform	24	3	−48	37	−4.7571

The significance level was set at for multiple comparisons corrected by Gaussian random field (GRF) theory (voxel significance: , cluster significance: ). Age, sex, and the mean FD values were used as covariates to minimize the potential effects of these variables. MNI: Montreal Neurological Institute; OFC: orbitofrontal cortex; MPFC: medial prefrontal cortex.