Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice

Figure 2

Learning and memory performance of in CD-1 mice in the MWM test. Latency (a), distance (b), and velocity (c) swam during the learning phase at different ages in the control groups. (d, e) Latency and distance during the learning phase by 3-month-old (3 M) and (f, g) 15-month-old (15 M) CD-1 mice in different treatment groups. The percent time (h) and distance (i) swam in the target quadrant in different treatment groups by 3 M and 15 M CD-1 mice. per group. . , compared with the control group; ^#, ^## compared with the LPS group. CON: untreated control group; LPS: lipopolysaccharide treatment group; E: group of mice exposed to EE; MWM: Morris water maze.

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