Research Article
Effect of Propionic Acid on Diabetes-Induced Impairment of Unfolded Protein Response Signaling and Astrocyte/Microglia Crosstalk in Rat Ventromedial Nucleus of the Hypothalamus
Figure 9
Metformin and PA influence on the level of astrocytic marker GFAP and tight junction protein ZO-1. Immunoblotting analysis of GFAP and ZO-1 in rat VMH: (a) representative immunoblots are shown and quantified using tubulin as a loading control for hypothalamus lysates. The bar graphs of (b) GFAP and (c) ZO-1 protein levels are presented as (n =6/group). Data are shown as ; vs. control, vs. T2DM, # vs. metformin administration, and @ vs. PA administration.
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