Astragaloside IV Alleviates Brain Injury Induced by Hypoxia via the Calpain-1 Signaling Pathway

Figure 9

AS-IV inhibits calpain-1 overexpression and attenuates hypoxia-induced oxidative stress and apoptosis in HT22 cells. (a) The cell viability of each group was detected by CCK-8 assay (; ). (b, c) Changes in SOD and MDA were detected with kits (; SOD, ; MDA, ). (d–f) Western blotting was used to detect caspase-3 and calpain-1 protein expression (; calpain-1, ; caspase-3, ). Data are presented as the . compared with the HMG group, ^## compared with the HMG + ASIV group.

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