Structural Alteration of Medial Temporal Lobe Subfield in the Amnestic Mild Cognitive Impairment Stage of Alzheimer’s Disease

Table 3

Results of the ANOVA test and multiple comparisons of bilateral ROIs’ GM densities of the three groups. The differences of the densities of the bilateral hippocampus, amygdala, and entorhinal cortex in the comparisons of AD-MCI-NC, AD-MCI, and AD-NC were statistically significant () but not that obvious in comparison with MCI-NC (); the differences of the density of the mammillary body were not notable in the random comparison between these three groups ().

	AD-MCI-NC		AD-MCI		AD-NC		NC-MCI
	value	value	value	value	value	value	value	value
L-AMYG	6.6793	0.0023	-3.1442	0.0033	-3.569	0.001	-0.1664	0.8684
R-AMYG	8.423	0.0006	-3.797	0.0005	-3.5467	0.0011	0.1902	0.8499
L-EC	4.8039	0.0114	-2.7972	0.0081	-2.8397	0.0074	-0.0532	0.9577
R-EC	4.8778	0.0107	-2.9915	0.0049	-2.6157	0.0129	-0.0082	0.9935
L-Hippo	7.3448	0.0013	-3.4393	0.0015	-3.5846	0.001	-0.3777	0.7071
R-Hippo	13.4588	1.3×10^-5	-4.7372	3.1×10^-5	-4.3955	0.1 ×10^-3	0.499	0.6197
L-MB	0.1364	0.8727	-0.1186	0.9062	0.2275	0.8213	-0.5567	0.58
R-MB	0.3072	0.7366	0.7232	0.4741	0.2941	0.7704	0.5729	0.569