Upregulation of PGC-1α Attenuates Oxygen-Glucose Deprivation-Induced Hippocampal Neuronal Injury

Figure 6

PGC-1α promotes the expression of mitochondrial antioxidants in hippocampal cells. (a) Representative images of SOD2 expression in HT-22 cells with or without PGC-1α overexpression after OGD treatment. (b) Representative images of Trx2 expression in HT-22 cells with or without PGC-1α overexpression after OGD treatment. (c) Representative images of Prx3 expression in HT-22 cells with or without PGC-1α overexpression after OGD treatment. (d) Quantification of the relative fluorescence intensity of SOD2, Trx2, and Prx3 using ImageJ software. ; per group.

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