Research Article

Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System

Figure 12

Role of miR-23-27-24 clusters in myelin formation. The miR-23-27-24 cluster enhances myelin growth in adults by negatively regulating LZTR1, promoting R-RAS expression, and activating the Mek/Erk1/2-MAPK pathway.