Research Article
Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice
Figure 1
The weight gain trends of ApoE-/- mice in our study. (a) Compared with the control groups, the remaining 4 groups (HFD, DC, SE, and DS groups) significantly increased their body weight after 8 weeks of high-fat diet feeding. Weight gain gradually decreased in the DC, SE, and DS groups from 28 weeks to 36 weeks of age. vs. the control group. #, $, and & vs. the HFD group. (b) Experimental design.
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