Electroacupuncture Zusanli (ST36) Relieves Somatic Pain in Colitis Rats by Inhibiting Dorsal Root Ganglion Sympathetic-Sensory Coupling and Neurogenic Inflammation

Figure 1

EA attenuated colitis severity and somatic hyperalgesia in DSS-induced colitis rats. (a) Schematic describing experimental design. The rats were gavaged with dextran sulfate sodium (DSS) saline solution for 4 days to establish a colitis rat model. Then, the rats in the Zusanli electroacupuncture (Zusanli-EA) group were treated with EA, once a day, for 21 consecutive days. (b–d) Disease activity index (DAI), thermal withdrawal latency (TWL), and mechanical withdrawal threshold (MWT) were measured at 7 days, 14 days, and 21 days in DSS-induced colitis rats. . vs. control group, ^# vs. sham-EA group, ^## vs. sham-EA group. Data represents .

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