Neural Plasticity

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells


Publishing date
23 Dec 2016
Status
Published
Submission deadline
05 Aug 2016

Lead Editor

1Southeast University, Nanjing, China

2University of Massachusetts Amherst, Amherst, USA

3Dalhousie University, Halifax, Canada

4University of Tampere, Tampere, Finland


Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells

Description

Hearing loss is considered the most common sensory disorder in human population that occurs at all ages worldwide and sensorineural hearing loss (SNHL) is the most common type of hearing loss. Various insults could induce the SNHL, including acoustic trauma, ear and brain tumors, aging, noise exposure, or ototoxic medications or chemicals. SNHL is caused by the irreversible loss of sensory hair cell and the degeneration of spiral ganglion neuron. SNHL is not yet curable because of the irreversible death of hair cells and the degeneration of spiral ganglion neurons in the cochlea. Recent years, exciting animal studies on signaling pathway manipulation, gene therapy, and stem cell transplantation as well as pharmaceutical agents demonstrated that hair cells and spiral ganglion neurons could be regenerated and indicated that hearing loss might eventually be curable in the future. Neural plasticity is the key feature for the spiral ganglion neurons and hair cells and is especially important for the new regenerated spiral ganglion neurons and hair cells. This special issue will focus on recent advances in reestablishing the neural plasticity of regenerated spiral ganglion neurons and sensory hair cells.

In this special issue, we invite authors to submit high-quality original research articles and reviews. Researchers and clinicians are encouraged to submit their work including both basic and translational research.

Potential topics include, but are not limited to:

  • Signaling mechanisms
  • Cytoskeletal regulation
  • Hair cell regeneration
  • Spiral ganglion neuron regeneration
  • Spiral ganglion neuron refinement and retraction
  • Spiral ganglion neuron neurites pruning
  • Application of biomaterials in improving the plasticity of spiral ganglion neuron
  • Ribbon synapse plasticity
  • Noise and drug induced changes in hair cell and spiral ganglion neuron plasticity
  • Genetic aspects regulating the plasticity

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 1807581
  • - Editorial

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells

Renjie Chai | Geng-Lin Li | ... | Jing Zou
  • Special Issue
  • - Volume 2017
  • - Article ID 8283075
  • - Research Article

Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses

Changquan Wang | Zhenmin Zhong | ... | Fangyi Chen
  • Special Issue
  • - Volume 2017
  • - Article ID 7416727
  • - Research Article

The Relative Weight of Temporal Envelope Cues in Different Frequency Regions for Mandarin Sentence Recognition

Yang Guo | Yuanyuan Sun | ... | Shankai Yin
  • Special Issue
  • - Volume 2016
  • - Article ID 2523458
  • - Review Article

Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation

Xiaoling Lu | Yilai Shu | ... | Huawei Li
  • Special Issue
  • - Volume 2016
  • - Article ID 9409846
  • - Research Article

Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo

Yilai Shu | Yong Tao | ... | Zheng-Yi Chen
  • Special Issue
  • - Volume 2016
  • - Article ID 5310192
  • - Research Article

Massively Parallel Sequencing of a Chinese Family with DFNA9 Identified a Novel Missense Mutation in the LCCL Domain of COCH

Xiaodong Gu | Wenling Su | ... | Huawei Li
  • Special Issue
  • - Volume 2016
  • - Article ID 5836143
  • - Research Article

Identification of a Novel ENU-Induced Mutation in Mouse Tbx1 Linked to Human DiGeorge Syndrome

Jiaofeng Chen | Xue Zhang | ... | Wei Xiong
  • Special Issue
  • - Volume 2016
  • - Article ID 6720420
  • - Research Article

Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice

Xiaolong Fu | Linqing Zhang | ... | Jiangang Gao
  • Special Issue
  • - Volume 2016
  • - Article ID 4545826
  • - Research Article

Synchronized Progression of Prestin Expression and Auditory Brainstem Response during Postnatal Development in Rats

Jianfeng Hang | Wenlu Pan | ... | Jie Tang
  • Special Issue
  • - Volume 2016
  • - Article ID 8648297
  • - Research Article

Effect of Endolymphatic Hydrops on Sound Transmission in Live Guinea Pigs Measured with a Laser Doppler Vibrometer

Chen-Ru Ding | Xin-Da Xu | ... | Dong-Dong Ren
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore6.900
Impact Factor3.093
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.