Neural Plasticity

Environmental Control of Adult Neurogenesis: From Hippocampal Homeostasis to Behavior


Status
Published

Lead Editor

1Department of Biomedicine, University of Bergen, Bergen, Norway

2National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA

3Swammerdam Institute for Life Sciences (SILS), Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands

4Swammerdam Institute for Life Sciences (SILS), Center for Neuroscience, University of Amsterdam, Amsterdam, The Netherlands


Environmental Control of Adult Neurogenesis: From Hippocampal Homeostasis to Behavior

Description

Neuroplasticity is the brain’s ability to change and adapt as a result of experience. Adult neurogenesis, neural stem and progenitor cells’ ability to generate new neurons in adulthood, is a form of structural plasticity with important implications for understanding brain development and potential use by the aged or injured brain to compensate for damaged or dysfunctional pathways.

The hippocampus, one of the few structures where adult neurogenesis occurs, is vital to cognitive and emotional processing. Plasticity here is highly responsive to environmental factors, and an individual’s behavioral and physiological traits can be lastingly affected by elements such as exercise, drugs, learning, or stress. Chronic stress is often associated with the development or exacerbation of psychiatric conditions. Environmental or stress-induced neural activity changes act in concert with genomic and nongenomic mechanisms to modulate changes in gene expression and structural and functional plasticity. As stress affects individuals differently, it is unclear why some thrive and others falter under similar conditions. The perception of stress and persistence of its consequences varies according to an individual’s stress resilience or vulnerability, but the underlying neural processes are largely unknown.

We invite investigators to submit original research and review articles that address this field. We encourage manuscripts that will stimulate efforts to understand the molecular and (epi)genetic mechanisms that define interactions between environmental stressors, hippocampal neuroplasticity, and disease. Papers addressing how these pathways underlie (mal)adaptive responses to stress or the development of novel strategies for therapeutic intervention or treatment of neuropathological conditions will be of great interest. Potential topics include, but are not limited to:

  • Environmental effects on hippocampal neuroplasticity/neurogenesis and their role in the development of anxiety and depressive-like behavior
  • Impact of stress or exercise occurring, for example, at different developmental periods, on adult hippocampal neuroplasticity/neurogenesis
  • Neural mechanisms of resilience or vulnerability to stress
  • Sex-dependent modulation of environmental and stress effects on hippocampal plasticity
  • Stress-induced epigenetic and transgenerational changes in the hippocampus

Before submission authors should carefully read over the journal’s Authors Guidelines, which are located at http://www.hindawi.com/journals/np/guidelines/. Prospective authors should submit an electronic copy of their manuscript through the Journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/np/csan/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 808643
  • - Editorial

Environmental Control of Adult Neurogenesis: From Hippocampal Homeostasis to Behavior and Disease

Sjoukje D. Kuipers | Clive R. Bramham | ... | Paul J. Lucassen
  • Special Issue
  • - Volume 2014
  • - Article ID 693851
  • - Research Article

Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition

Michael W. Marlatt | Jan Bauer | ... | Paul J. Lucassen
  • Special Issue
  • - Volume 2014
  • - Article ID 959154
  • - Research Article

Hippocampal Proliferation Is Increased in Presymptomatic Parkinson’s Disease and due to Microglia

Karlijn J. Doorn | Benjamin Drukarch | ... | Paul J. Lucassen
  • Special Issue
  • - Volume 2014
  • - Article ID 497657
  • - Review Article

The Interplay between Reproductive Social Stimuli and Adult Olfactory Bulb Neurogenesis

Paolo Peretto | Roberta Schellino | ... | Aldo Fasolo
  • Special Issue
  • - Volume 2014
  • - Article ID 454696
  • - Review Article

Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity

Martin Regensburger | Iryna Prots | Beate Winner
  • Special Issue
  • - Volume 2014
  • - Article ID 723915
  • - Review Article

Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations

Peter Rotheneichner | Simona Lange | ... | Sebastien Couillard-Despres
  • Special Issue
  • - Volume 2014
  • - Article ID 563160
  • - Review Article

Effects of Diet on Brain Plasticity in Animal and Human Studies: Mind the Gap

Tytus Murphy | Gisele Pereira Dias | Sandrine Thuret
  • Special Issue
  • - Volume 2014
  • - Article ID 194396
  • - Review Article

Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation

Ksenia Musaelyan | Martin Egeland | ... | Sandrine Thuret
  • Special Issue
  • - Volume 2014
  • - Article ID 574159
  • - Review Article

The Maternal Brain: An Organ with Peripartal Plasticity

Katharina Maria Hillerer | Volker Rudolf Jacobs | ... | Ludwig Aigner
  • Special Issue
  • - Volume 2014
  • - Article ID 541870
  • - Review Article

Adult Neuroplasticity: More Than 40 Years of Research

Eberhard Fuchs | Gabriele Flügge
Neural Plasticity
 Journal metrics
Acceptance rate53%
Submission to final decision58 days
Acceptance to publication37 days
CiteScore6.900
Impact Factor3.093
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