Neural Plasticity

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018


Publishing date
01 Aug 2018
Status
Published
Submission deadline
23 Mar 2018

Lead Editor

1Southeast University, Nanjing, China

2University of Massachusetts Amherst, Amherst, USA

3Dalhousie University, Halifax, Canada

4Tulane University, New Orleans, USA


Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018

Description

Hearing loss is considered the most common sensory disorder in human population which occurs at all ages worldwide and sensorineural hearing loss (SNHL) is the most common type of hearing loss. Various insults could induce the SNHL, including acoustic trauma, ear and brain tumors, aging, noise exposure, or ototoxic medications or chemicals. SNHL is caused by the irreversible loss of sensory hair cell and the degeneration of spiral ganglion neuron. SNHL is not yet curable because of the irreversible death of hair cells and the degeneration of spiral ganglion neurons in the cochlea. In the recent years, exciting animal studies on signaling pathway manipulation, gene therapy, and stem cell transplantation as well as pharmaceutical agents demonstrated that hair cells and spiral ganglion neurons could be regenerated and indicated that hearing loss might eventually be curable in the future. Neural plasticity is the key feature for the spiral ganglion neurons and hair cells and is especially important for the new regenerated spiral ganglion neurons and hair cells. This special issue will focus on recent advances in reestablishing the neural plasticity of regenerated spiral ganglion neurons and sensory hair cells.

In this special issue, we invite authors to submit high-quality original research articles and reviews. Researchers and clinicians are encouraged to submit their work including both basic and translational research.

Potential topics include but are not limited to the following:

  • Signaling mechanisms
  • Cytoskeletal regulation
  • Hair cell regeneration
  • Spiral ganglion neuron regeneration
  • Spiral ganglion neuron refinement and retraction
  • Spiral ganglion neuron neurites pruning
  • Application of biomaterials in improving the plasticity of spiral ganglion neuron
  • Ribbon synapse plasticity
  • Noise and drug induced changes in hair cell and spiral ganglion neuron plasticity
  • Genetic aspects regulating the plasticity

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 4759135
  • - Editorial

Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018

Renjie Chai | Geng-Lin Li | ... | Hai Huang
  • Special Issue
  • - Volume 2018
  • - Article ID 7513258
  • - Research Article

The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns

Shaofeng Liu | Yunfeng Wang | ... | Wenyan Li
  • Special Issue
  • - Volume 2018
  • - Article ID 1970150
  • - Research Article

Postnatal Development of Microglia-Like Cells in Mouse Cochlea

Penghui Chen | Yongchuan Chai | ... | Hao Wu
  • Special Issue
  • - Volume 2018
  • - Article ID 7502648
  • - Research Article

Hydromechanical Structure of the Cochlea Supports the Backward Traveling Wave in the Cochlea In Vivo

Fangyi Chen | Dingjun Zha | ... | Alfred Nuttall
  • Special Issue
  • - Volume 2018
  • - Article ID 3989201
  • - Research Article

N-Methyl-D-Aspartate Receptors Involvement in the Gentamicin-Induced Hearing Loss and Pathological Changes of Ribbon Synapse in the Mouse Cochlear Inner Hair Cells

Juan Hong | Yan Chen | ... | Peidong Dai
  • Special Issue
  • - Volume 2018
  • - Article ID 3170801
  • - Review Article

Inner Ear Hair Cell Protection in Mammals against the Noise-Induced Cochlear Damage

Muhammad Waqas | Song Gao | ... | Wenyan Li
  • Special Issue
  • - Volume 2018
  • - Article ID 4372913
  • - Research Article

Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear

Peipei Li | Zongzhuang Wen | ... | Jiangang Gao
  • Special Issue
  • - Volume 2018
  • - Article ID 4920980
  • - Research Article

Genetic Etiology Study of Ten Chinese Families with Nonsyndromic Hearing Loss

Songqun Hu | Feifei Sun | ... | Luping Zhang
  • Special Issue
  • - Volume 2018
  • - Article ID 3786489
  • - Research Article

Comparison of Acceptable Noise Level Generated Using Different Transducers and Response Modes

Liang Xia | Jingchun He | ... | Shankai Yin
  • Special Issue
  • - Volume 2018
  • - Article ID 7691473
  • - Review Article

The Role of Autoimmunity in the Pathogenesis of Sudden Sensorineural Hearing Loss

Guangfei Li | Dan You | ... | Shan Sun
Neural Plasticity
 Journal metrics
Acceptance rate43%
Submission to final decision68 days
Acceptance to publication43 days
CiteScore3.330
Impact Factor3.591
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