Diabetic Neuropathy: A Clinical and Neuropathological Study of 107 Patients

Table 1

Clinical Characteristics of 107 Patients and Diabetic Neuropathy.

Study Cohort	Number	Percentages
Women	36	34
Men	71	66
Mean Age 64.7 years
(Range 31–95 years)
Clinical Neuropathic Syndrome
MNM	1	1
DLRPN	35	33
DSPN	71	66
Histological Severity of Neuropathy
Normal	1	1
Mild	17	16
Moderate	54	50
Severe	35	33
Teased Fiber/Semithin Section Analysis
Normal	1	1
Axonopathy	45	65
Myelinopathy	23	35
Cellular Response
Perivasculitis	26	23
Microvasculitis	3	3
Necrotizing arteritis	3	3
Complement Immunofluorescence
C3 deposition	70	67
C5b-9	65	62
Other Findings
Onion bulb formation	10	9
Epineurial vascular thrombosis	5	5