Eye Movement Impairment Recovery in a Gaucher Patient Treated with Miglustat

Table 1

Eye movement characteristic parameters in the two GD sisters (A. I. and F. I.) compared to mean values and SD of 10 normal subjects (and corresponding confidence interval at 𝑃=.05). 𝐴/𝐷𝑚: slope of the amplitude/duration linear relationship; 𝐴/𝐷𝑞: intercept of the amplitude/duration linear relationship; 𝐴/𝑉_𝑝   1/𝛼: velocity saturation value of the non linear amplitude/peak velocity relationship; 𝐴/𝑉_𝑝  1/𝛽: slope at the lowest amplitude of the non linear amplitude/peak velocity relationship; 𝐴/𝐾𝑚𝑘: slope of the linear amplitude/𝐾 ratio relationship; 𝐴/𝑆𝐾𝑚𝑠: slope of the linear amplitude/skewness relationship.

		𝐴/𝐷𝑚	𝐴/𝐷𝑞	𝐴/𝑉𝑝   1/𝛼	𝐴/𝑉𝑝   1/𝛽	Latency	𝐴/𝐾𝑚𝑘	𝐴/𝑆𝐾𝑚𝑠
		ms/deg	𝑚𝑠	deg/s	1/s	𝑚𝑠	1/deg	1/deg
A. I.	2000	2.77	29	646	75	174	0.0041	−0.028
	2005	2.61	31	628	63	198	0.0040	−0.026
	2007	2.48	33	881	69	173	0.0015	−0.005
F. I.	2000	2.69	46	570	56	191	0.0031	−0.019
	2005	8.77	50	259	56	203	−0.0002	−0.0006
	2007	2.52	30	851	53	199	−0.0007	0.0014
Normal Subjects	mean	1.86	36	1282	61	188	0.0023	−0.013
	SD	0.47	5	355	15	36	0.0022	0.011
Conf. Int. (𝑃=.05)	min	0.86	25	524	28	111	−0.003	−0.036
	max	2.86	47	2040	93	265	0.0072	0.01