Research Article

Infections and Ischemic Stroke Outcome

Table 2

Characteristics of patients with or without an in-hospital infection.

Characteristics Pneumonia or UTI ( )No infection ( )P
Value Value

Baseline characteristics
Age, mean, SD (years)61876.1 ± 10.6121569.2 ± 12.4<.001
Gender (male), (%)619201 (32.5)1219641 (52.6)<.001
Premorbid mRS 3–5, (%)61695 (15.4)121683 (6.8)<.001
History of stroke, (%)614114 (18.6)1203169 (14.0).014
Hypertension, (%)614456 (74.3)1215896 (73.7).822
Atrial fibrillation, (%)613234 (38.2)1210279 (23.1)<.001
Heart failure, (%)604193 (32.0)1209223 (18.4)<.001
CAD, (%)613247 (40.3)1211398 (32.9).002
Diabetes, (%)613158 (25.8)1209239 (19.8).004
Nicotine use (5 years), (%)615125 (20.3)1206351 (29.1)<.001
Etiology of IS (TOAST) 616 1213
 Atherothrombotic, (%)93 (15.1)114 (9.4).543
 Cardioembolic, (%)209 (33.9)275 (22.7)<.001
 Lacunar, (%)61 (9.9)282 (23.2)<.001
Diffuse lesion (≥1 lobe)408211 (51.7)701173 (24.7)<.001
TACI, (%)616192 (31.2)1213114 (9.4)<.001
Admission SSS, mean, SD61723.4 ± 16.1121839.3 ± 15.4<.001
Body temperature day 1, mean (°C)57436.8 ± 0.52114936.7 ± 0.37<.001
Mean week body temperature (°C)61636.9 ± 1.27120836.7 ± 0.79<.001

Outcome
Recurrent stroke, (%)61914 (2.3)121915 (1.2).113
30-day SSS, mean, SD42436.7 ± 15.9113949.6 ± 10.3<.001
30-day mortality, (%)619192 (31.0)121989 (7.3)<.001
30-day death or dependency, (%)599504 (84.1)1209453 (37.5)<.001
90-day mortality, (%)534274 (51.3)1066130 (12.2)<.001
90-day death or dependency, (%)502405 (80.7)1011338 (33.4)<.001

UTI: urinary tract infection; : the number of patients with available data; SD: standard deviation; mRS: modified Rankin Scale; CAD: coronary artery disease; TACI: total anterior circulation infarction; IS: ischemic stroke; TOAST: Trial of Org 10172 in Acute Stroke Treatment; SSS: Scandinavian Stroke Scale.