Subarachnoid Transplant of the Human Neuronal hNT2.19 Serotonergic Cell Line Attenuates Behavioral Hypersensitivity without Affecting Motor Dysfunction after Severe Contusive Spinal Cord Injury
Table 3
ANOVA showing BBB scores.
Time after contusion
Group 1: laminectomy
Group 2: contusion
Group 3: contusion + hNT2-6
Group 4: contusion + hNT2-19
Group 5: laminectomy + hNT-19
Group 6: laminectomy +hNT2-6
One way ANOVA
Mean (SEM)
Mean (SEM)
Mean (SEM)
Mean (SEM)
Mean (SEM)
Mean (SEM)
-statistic, value
Baseline
21.0 (0.00)
21.0 (0.00)
21.0 (0.00)
21.0 (0.00)
21.0 (0.00)
21.0 (0.00)
NA
Day 1
16.67 (3.28)
0.29 (0.10)
0.58 (0.58)
0.67 (0.32)
21.0 (0.00)
21.0 (0.00)
73.0;
Week 1
17.25 (2.71)
4.36 (1.39)
3.67 (1.41)
2.83 (0.80)
21.0 (0.00)
21.0 (0.00)
44.6;
Week 2
17.75 (2.78)
7.29 (1.37)
6.00 (1.53)
5.89 (1.07)
21.0 (0.00)
21.0 (0.00)
27.4;
Week 3
17.92 (2.62)
7.71 (1.15)
6.08 (1.58)
7.28 (1.05)
20.4 (1.34)
20.5 (0.50)
24.9;
Week 4
18.83 (2.17)
9.29 (0.65)
7.75 (1.45)
7.17 (1.41)
21.0 (0.00)
19.8 (0.99)
23.6;
Week 5
18.83 (2.17)
9.29 (0.64)
8.17 (1.45)
7.28 (1.50)
21.0 (0.00)
20.6 (0.43)
25.1;
Week 6
18.83 (2.17)
9.57 (0.57)
8.92 (0.85)
7.67 (1.53)
21.0 (0.00)
20.6 (0.43)
25.9;
Week 7
18.92 (2.08)
9.86 (0.46)
8.75 (1.03)
7.28 (1.46)
21.0 (0.00)
21.0 (0.00)
30.3;
Week 8
18.92 (2.08)
9.86 (0.46)
8.50 (1.33)
7.83 (1.45)
21.0 (0.00)
21.0 (0.00)
27.3;
Post hoc analyses (Bonferroni): Group 1 is significantly different than Groups 2, 3, 4 on all time points. Group 2 is significantly different than Groups 1, 5, 6 on all time points. Group 3 is significantly different than Groups 1, 5, 6 at all time points. Group 4 is significantly different than Groups 1, 5, 6 at all time points. Group 5 is significantly different than groups 2, 3, 4 on all time points. Group 6 is significantly different than groups 2, 3, 4 on all time points.
