DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease
Table 5
Pearson’s correlation between volumetric and diffusion MR indexes.
Volumetric variable
Diffusion variable
CTRL ()
MCI ()
AD ()
Volume brain tissue
MD brain tissue
0.001
<0.001
n.s.
Volume grey matter
MD grey matter
0.001
0.008
n.s.
Volume left PC/PCC
MD left PC/PCC
n.s.
0.014
n.s.
Volume right PC/PCC
MD right PC/PCC
n.s.
0.004
0.004
Volume left hippocampus
MD left hippocampus
n.s.
0.001
0.002
Volume right hippocampus
MD right hippocampus
n.s.
0.003
n.s.
Volume left hipp-PC/PCC
FA right hippocampus
0.036
n.s.
n.s.
MD left hipp-PC/PCC
<0.001
<0.001
0.002
FA left hipp-PC/PCC
<0.001
0.015
n.s.
Volume right hipp-PC/PCC
MD right hipp-PC/PCC
<0.001
<0.001
n.s.
FA right hipp-PC/PCC
0.004
0.002
n.s.
Statistical analysis: 2-tailed Pearson’s correlation; is considered significant. Only significant correlations were reported. MCI: mild cognitive impairment; AD: Alzheimer’s Disease; n.s.: not significant; Hipp-PC/PCC: hippocampus to PC/PCC tract.
