Structural Angle and Power Images Reveal Interrelated Gray and White Matter Abnormalities in Schizophrenia

Table 1

Talairach labels for regions detected by VBM. Voxels above a threshold of |𝑍|>3.0 were converted from Montreal Neurological Institute (MNI) coordinates to Talairach coordinates and entered into a database to assign anatomic labels for the left (L) and right (R) hemispheres. The concentration of voxels in each area is provided in cubic centimeters (cc). The areas with volume above 1.0 are listed. Within each area, the maximum 𝑍 value and its coordinate are provided.

Angle	Brodmann area	L/R volume (cc)	L/R random effects: max𝑍(𝑥,𝑦,𝑧)
Thalamus		6.0/6.7	6.3(1,−13,2)/6.5(−3,−9,−3)
Insula	13, 47, 41	6.9/2.4	5.9(−1,−7,2)/4.5(3,−3,−7)
Middle, superior and inferior occipital gyri	19, 37, 18	8.2/11.3	4.6(−31,4,−17)/5.7(1,−3,−2)
Anterior cingulate	25, 32, 24, 10	1.9/2.8	5.7(1,−15,−3)/4.0(34,5,−18)
Inferior, superior, medial, and middle frontal gyri	47, 13, 44, 45, 11, 46, 9, 10, 6, 8	32.5/26.9	5.4(7,−6,−5)/5.2(−1,−16,6)
Claustrum		4.8/1.5	5.2(3,−3,3)/4.2(−39,−17,12)
Inferior parietal lobule	40, 39	4.5/2.6	5.0(−7,−43,42)/4.1(−61,18,9)
Cingulate gyrus	31, 24, 32	4.5/6.0	5.0(−15,−76,−14)/4.7(−34,13,2)
Parahippocampal gyrus	34, Amygdala, 27, 36, 28, 35, 19	1.9/2.8	5.0(10,−9,5)/3.9(−27,−15,12)
Lentiform nucleus		3.7/1.7	4.9(−30,11,−18)/4.7(3,51,−9)
Postcentral gyrus	43, 40, 2, 1, 3, 7, 6, 13, 4, 44	6.2/5.0	4.8(−6,−13,−6)/4.5(45,−73,33)
Cuneus and precuneus	19, 18, 17, 7, 39, 31	9.2/9.1	4.7(9,−4,42)/4.7(−27,−75,−15)
Angular gyrus	39	1.5/1.1	4.2(−13,−84,−25)/4.7(7,0,0)
Supramarginal gyrus	40	2.2/1.3	4.6(−34,14,−6)/3.6(−4,−25,3)
Superior, inferior and middle temporal gyri	38, 42, 22, 41, 13, 39, 21,19, 20, 37	13.4/12.9	4.6(−1,50,29)/4.3(−22,46,45)
Inferior semilunar lobule		9.1/2.8	4.5(−9,−80,−24)/3.8(−1,−55,8)
Cerebellar tonsil		11.4/1.1	4.5(−59,−69,−2)/3.5(−7,−10,10)
Paracentral lobule	31, 6, 5	2.2/0.6	4.3(30,−75,−15)/3.3(9,−66,46)
Cerebellar vermis		19.5/7.3	5.3(1,−19,2)/4.3(50,−77,29)
Lingual gyrus	18, 19	1.9/0.2	4.0(−37,−79,27)/3.5(67,−44,20)
Fusiform gyrus	37, 18, 19, 20	3.2/1.5	3.6(39,−7,−19)3.6(−53,−60,−10)
Power	Brodmann area	L/R volume (cc)	L/R random effects: max𝑍(𝑥,𝑦,𝑧)
Claustrum		3.2/3.0	5.8(−34,5,−9)/4.5(−45,16,−10)
Inferior, superior, medial and middle Frontal gyri	13, 47, 11, 10, 45, 46, 47, 44, 9, 25, 6, 8	38/59.3	5.6(−34,13,−3)/4.8(−40,10,−7)
Insula	13, 40	5.2/4.8	5.6(−36,1,−3)/5.1(−30,8,−12)
Superior temporal gyrus	38, 22, 41, 13	14.3/16.6	5.0(−37,−3,2)/4.3(−45,−15,−41)
Inferior semilunar lobule		9.1/3.5	4.6(−52,14,−7)/3.8(−34,54,−3)
Parahippocampal gyrus	34, Amygdala, 36, 35, 27, 30	0.9/1.7	4.5(30,29,−23)/4.1(6,54,6)
Middle and inferior temporal gyri	21, 38, 39, 37, 19, 20, 25	6.7/5.0	4.4(−25,14,−15)/3.7(−22,−79,−33)
Cerebellar tonsil		2.4/1.1	4.2(24,28,−24)/3.4(−3,54,22)
Anterior cingulate	32, 25	1.9/1.9	3.6(3,46,−6)/3.9(−22,−59,−46)
Cerebellar vermis		6.4/4.9	4.3(−36,2,5)/4.1(−49,9,−2)
Precentral and postcentral gyri	3, 7, 43, 40, 1, 44, 6, 13	6.9/5.4	3.7(−33,−72,−39)/3.6(−6,44,1)